EBV INFECTION OF PRIMARY COLONIC EPITHELIAL CELLS CAUSES INFLAMMATION, DDR AND AUTOPHAGY DYSREGULATION, EFFECTS THAT MAY PREDISPOSE TO IBD AND CARCINOGENESIS

EBV is a gammaherpesvirus strongly associated to human cancer.The virus has been shown to play a role also in inflammatory diseases, including IBD, in the context Flashlights of which colon cancer more frequently arise.In this study, we show for the first time that EBV infects primary colonic epithelial cells (HCoEpC), promotes pro-inflammatory cyt

Microsporogenesis was analyzed in an interspecific hybrid between an artificially tetraploidized sexual accession of Brachiaria ruziziensis (R genome) and a natural apomictic tetraploid accession of B.brizantha (B genome).Chromosomes associated predominantly as bivalents.From Collectible this phase to the end of meiosis, chromosomes presented irreg

Abstract The tight correlation between topologically associating domains (TADs) and epigenetic domains in Drosophila suggests that the epigenome contributes Collectible to define TADs.However, it is still unknown whether histone modifications are essential for TAD formation and structure.By either deleting or shifting key regulatory elements needed